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Corson Lab Publications

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47. Lee H, Yuan Y, Rhee I, Corson TW, Seo SY. 2016. Synthesis of natural homoisoflavonoids having either 5,7-dihydroxy-6-methoxy or 7-hydroxy-5,6-dimethoxy groups. Molecules, 21, 1058. [Full text] [PDF]

46. Lee B, Sun W, Lee H, Basavarajappa HD, Sulaiman RS, Sishtla K, Fei X, Corson TW, Seo SY. 2016. Design, synthesis and biological evaluation of photoaffinity probes of antiangiogenic homoisoflavonoids. Bioorganic & Medicinal Chemistry Letters, 26, 4277–4281. [Full text] [PDF]

45. Racher H, Soliman S, Argiropoulos B, Chan HSL, Gallie BL, Perrier R, Matevski D, Rushlow D, Piovesan B, Shaikh F, MacDonald H, Corson TW. 2016. Molecular analysis distinguishes metastatic disease from second cancers in patients with retinoblastoma. Cancer Genetics, 209, 359–363. [Full text] [PDF]

44. O’Hare MN, Shadmand M, Sulaiman RS, Sishtla K, Sakisaka T, Corson TW. 2016. Kif14 overexpression accelerates murine retinoblastoma development. International Journal of Cancer, 139, 1752–1758[Full text] [PDF]

43. Sulaiman RS, Merrigan S, Quigley J, Boulton ME, Kennedy B, Seo SY, Corson TW. 2016. A small molecule pharmacotherapy ameliorates ocular neovascularization without toxicity. Scientific Reports, 6, 25509[Full text] [PDF]

42. Dimaras H, Corson TW. 2016. The molecular genetics of retinoblastoma. Reviews in Cell Biology and Molecular Medicine, 2, 105–142. [Full text]

41. Dimaras H, Corson TW, Cobrinik D, White A, Zhao J, Munier FL, Abramson DH, Shields CL, Chantada GL, Njuguna F, Gallie BL. 2015. Retinoblastoma. Nature Reviews Disease Primers, Article number: 15021, doi:10.1038/nrdp.2015.21. [Full text]

40. Basavarajappa HD*, Lee B*, Lee H, Sulaiman RS, An H, Magaña C, Shadmand M, Vayl A, Rajashekhar G, Kim E-Y, Suh Y-G, Lee K, Seo S-Y*, Corson TW*. 2015. Synthesis and biological evaluation of novel homoisoflavonoids for retinal neovascularization. Journal of Medicinal Chemistry, 58, 5015–5027. *equal contributors. [Full text] [PDF]

39. Sulaiman RS, Quigley J, Qi X, O'Hare MN, Grant MB, Boulton ME, Corson TW. 2015. A simple optical coherence tomography quantification method for choroidal neovascularization. Journal of Ocular Pharmacology and Therapeutics, 31, 447–54. [Full text] [PDF] 

38. Hill JA, Lee SY, Njambi L, Corson TW, Dimaras H. 2015. Cancer genetics education in a low- to middle-income country: Evaluation of an interactive workshop for clinicians in Kenya. PLoS ONE, 10, e0129852. [Full text] [PDF]

37. Wenzel AA, O’Hare MN, Shadmand M, Corson TW. 2015. Optical coherence tomography enables imaging of tumor initiation in the TAg-RB mouse model of retinoblastoma. Molecular Vision, 21, 515–522. [Full text] [PDF]

36. Sulaiman RS, Basavarajappa HD, Corson TW. 2014. Natural product inhibitors of ocular angiogenesis. Experimental Eye Research, 129, 161–171. [Full text] [PDF]

35. Lee B, Basavarajappa HD, Sulaiman RS, Fei X, Seo S-Y*, Corson TW*. 2014. First synthesis of the antiangiogenic homoisoflavanone, cremastranone. Organic and Biomolecular Chemistry, 12, 7673–7677. *equal contributors. [Full text] [PDF]

34. Luo N, Conwell MD, Chen X, Cantor LB, Wells CD, Kettenhofen CI, Westfall CJ, Weinreb RN, Corson TW, Spandau DF, Gattone VG, Iomini C, Obukhov AG, Sun Y. 2014. Primary cilia signaling mediates intraocular pressure sensation. Proceedings of the National Academy of Sciences of the USA, 111, 12871–12876. [Full text] [PDF]

33. Corson TW, Samuels BC, Wenzel AA, Geary AJ, Riley AA, McCarthy BP, Hanenberg H, Bailey BJ, Rogers PI, Pollok KE, Rajashekhar G, Territo PR. 2014. Multimodality imaging methods for assessing retinoblastoma orthotopic xenograft growth and development. PLoS ONE, 9, e99036. [Full text] [PDF]

32. Singel SM, Cornelius C, Zaganjor E, Batten K, Sarode VR, Buckley DL, Peng Y, John GB, Li HC, Sadeghi N, Wright WE, Lum L, Corson TW, Shay JW. 2014. KIF14 promotes AKT phosphorylation and contributes to chemoresistance in triple-negative breast cancer. Neoplasia, 16, 247–256. [Full text] [PDF]

31. Basavarajappa HD*, Lee B*, Fei X, Lim D, Callaghan B, Mund JA, Case J, Rajashekhar G, Seo SY*, Corson TW*. 2014. Synthesis and mechanistic studies of a novel homoisoflavanone inhibitor of endothelial cell growth. PLoS ONE, 9, e95694. *equal contributors. [Full text] [PDF]

30. Thériault BL, Basavarajappa HD, Lim H, Pajovic S, Gallie BL*, Corson TW*. 2014. Transcriptional and epigenetic regulation of KIF14 overexpression in ovarian cancer. PLoS ONE, 9, e91540. *equal contributors. [Full text] [PDF]

29. Thériault BL, Dimaras H, Gallie BL, Corson TW. 2014. The genomic landscape of retinoblastoma: a review. Clinical and Experimental Ophthalmology, 42, 33–52. [Full text] [PDF]

28. Hines J, Gough JD, Corson TW, Crews CM. 2013. Posttranslational protein knockdown coupled to receptor tyrosine kinase activation with phosphoPROTACs. Proceedings of the National Academy of Sciences of the USA, 110, 8942–8947. [Full text] [PDF]

27. Rushlow DE, Mol BM, Kennett JY, Yee S, Pajovic S, Thériault BL, Prigoda-Lee NL, Spencer C, Dimaras H, Corson TW, Pang R, Massey C, Godbout R, Jiang Z, Zacksenhaus E, Paton K, Moll AC, Houdayer C, Raizis A, Halliday W, Lam WL, Boutros PC, Lohmann D, Dorsman JC, Gallie BL. 2013. Characterization of retinoblastoma tumours without RB1 mutations: genomic, gene expression and clinical studies. Lancet Oncology, 14, 327–334. [Full text] [PDF]

26. Thériault BL & Corson TW. 2012. KIF14 (kinesin family member 14). Atlas of Genetics & Cytogenetics in Oncology & Haematology, 16, 695–699. [Full text] [PDF]

25. Basavarajappa HD, Corson TW. 2012. KIF14 as an oncogene in retinoblastoma: a target for novel therapeutics? Future Medicinal Chemistry, 4, 2149–52. [Full text] [PDF]

24. Temming P, Corson TW, Lohmann D. 2012. Retinoblastoma tumorigenesis: genetic and epigenetic changes walk hand in hand. Future Oncology, 8, 525–528. [Full text] [PDF]

23. Shah AS, Ramasubramanian A, Corson TW. 2012. Prenatal diagnosis & genetics. In Retinoblastoma, ed. Ramasubramanian A, Shields CL. New Delhi: Jaypee Brothers Medical Publisher. [Purchase]

22. Corson TW, Pajovic S, Dimaras H, Thériault BL, Gallie BL. 2012. Author response: Does the time of inactivation of pRb determine the cell of origin of retinoblastoma? Investigative Ophthalmolology & Visual Science, 53:676. [Full text] [PDF]

21. Pajovic S*, Corson TW*, Spencer C, Dimaras H, Orlic-Milacic M, Marchong MN, To KH, Thériault B, Auspitz M, Gallie BL. 2011. The TAg-RB murine retinoblastoma cell of origin has immunohistochemical features of differentiated Müller glia with progenitor properties. Investigative Ophthalmolology & Visual Science, 52:7618–7624. *equal contributors. [Full text] [PDF]

20. Neklesa TK*, Tae HS*, Schneekloth AR, Stulberg, MJ, Corson TW, Sundberg TB, Raina K, Holley SS & Crews CM. 2011. Small-molecule hydrophobic tagging-induced degradation of HaloTag fusion proteins. Nature Chemical Biology, 7:538–543. *equal contributors. [Full text] [PDF]

19. Corson TW, Cavga H, Aberle N & Crews CM. 2011. Triptolide directly inhibits dCTP pyrophosphatase. ChemBioChem, 12:1767–1773. corresponding author. [Full text] [PDF]

18. Uemura T, Green M, Corson TW, Perova T, Li PP & Warsh JJ. 2011. Bcl-2 SNP rs956572 associates with disrupted intracellular calcium homeostasis in bipolar I disorder. Bipolar Disorders, 13:41–51. [Full text] [PDF]

17. Buckley DL, Corson TW, Aberle N & Crews CM. 2011. HIV protease-mediated activation of sterically capped proteasome inhibitors and substrates. Journal of the American Chemical Society, 133:698–700. [Full text] [PDF]

16. Corson TW. 2010. Medichem — BIT Life Sciences’ First Annual International Conference. IDrugs 13:453–456. [Full text] [PDF]

15. Corson TW*, Aberle N* & Crews CM. 2008. Design and applications of bifunctional small molecules: why two heads are better than one. ACS Chemical Biology 3:677–692.
*equal contributors. [Full text] [PDF]

14. Dimaras H, Khetan V, Halliday W, Orlic M, Prigoda NL, Piovesan B, Marrano P, Corson TW, Prigoda N, Piovesan B, Eagle RC Jr, Squire JA & Gallie BL. 2008. Loss of RB1 induces non-proliferative retinoma: increasing genomic instability correlates with progression to retinoblastoma. Human Molecular Genetics, 17:1363–1372. [Full text] [PDF]

13. Huang JC*, Babak T*, Corson TW, Chua G, Khan S, Gallie BL, Hughes TR, Blencowe BJ, Frey BJ & Morris QD. 2007. Using expression profiling data to identify human microRNA targets. Nature Methods, 4:1045-1049.
*equal contributors. [Full text] [PDF]

12. Corson TW & Crews CM. 2007. Molecular understanding and modern application of traditional medicines: triumphs and trials. Cell, 130:769-774. [Full text] [PDF]

11. Madhavan J, Coral K, Mallikarjuna K, Corson TW, Amit N, Khetan V, George R, Biswas J, Gallie BL & Kumaramanickavel G. 2007. High expression of KIF14 in retinoblastoma: association with older age at diagnosis. Investigative Ophthalmology & Visual Science, 48:4901-4906. [Full text] [PDF]

10. Corson TW, Zhu CQ, Lau S, Shepherd FA, Tsao M-S & Gallie BL. 2007. KIF14 messenger RNA expression is independently prognostic for outcome in lung cancer. Clinical Cancer Research, 13:3229-3234. [Full text] [PDF]

9. Corson TW & Gallie BL. 2007. One hit, two hits, three hits, more? Genomic changes in the development of retinoblastoma. Genes, Chromosomes and Cancer, 46:617-634. [Full text] [PDF]

8. Bowles E*, Corson TW*, Bayani J, Squire JA, Wong N, Lai PB-S & Gallie BL. 2007. Profiling genomic copy number changes in retinoblastoma beyond loss of RB1. Genes, Chromosomes and Cancer 46:118-129. *equal contributors. [Full text] [PDF]

7. Corson TW & Gallie BL. 2006. KIF14 mRNA expression is a predictor of grade and outcome in breast cancer. International Journal of Cancer 119:1088-1094. [Full text] [PDF]

6. Spencer C, Pajovic S, Devlin H, Dinh Q-D, Corson TW & Gallie BL. 2005. Distinct patterns of expression of the RB gene family in mouse and human retina. Gene Expression Patterns 5:687-694. [Full text]

5. Corson TW, Huang A, Tsao M-S & Gallie BL. 2005. KIF14 is a candidate oncogene in the 1q minimal region of genomic gain in multiple cancers. Oncogene 24:4741-4753. [Full text] [PDF]

4. Marchong MN, Chen D, Corson TW, Lee C, Harmandayan M, Bowles E, Chen N & Gallie BL. 2004. Minimal 16q genomic loss implicates cadherin-11 in retinoblastoma. Molecular Cancer Research 2:495-503. [Full text] [PDF]

3. Wasserman MJ, Corson TW, Li PP, Sibony D, Pennefather P & Warsh JJ. 2004. Chronic lithium treatment attenuates intracellular calcium mobilization. Neuropsychopharmacology 29:759-769. [Full text] [PDF]

2. Corson TW, Woo KK, Li PP & Warsh JJ. 2004. Cell-type specific regulation of calreticulin and Bcl-2 expression by mood stabilizer drugs. European Neuropsychopharmacology 14:143-150. [Full text]

1. Corson TW, Li PP, Kennedy JL, Macciardi F, Cooke RG, Parikh SV & Warsh JJ. 2001. Association analysis of G-protein β3 subunit gene in bipolar disorder. Molecular Psychiatry 6:125-126. [Full text] [PDF]

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